Bactrim DS 800/160, a combination medication containing sulfamethoxazole and trimethoprim, is a widely prescribed antibiotic used to treat various bacterial infections. As a domain-specific expert with extensive knowledge in pharmacology, I will provide an in-depth analysis of its uses, side effects, and precautions, ensuring that the information is accurate, reliable, and easily accessible.
What is Bactrim DS 800⁄160?
Bactrim DS 800⁄160 is a double-strength formulation of the antibiotic combination sulfamethoxazole and trimethoprim. It is primarily used to treat urinary tract infections (UTIs), respiratory infections, and certain types of diarrhea. The medication works by inhibiting the growth of bacteria, thereby eliminating the infection.
Uses of Bactrim DS 800⁄160
Bactrim DS 800⁄160 is effective against a range of bacterial infections, including:
- Urinary tract infections (UTIs)
- Ear infections (otitis media)
- Bronchitis and pneumonia
- Diarrhea caused by bacterial infections
- Shigellosis (dysentery)
Side Effects of Bactrim DS 800⁄160
Like all medications, Bactrim DS 800⁄160 can cause side effects, some of which can be severe. Common side effects include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
Less common but more serious side effects may include:
- Allergic reactions (hives, itching, swelling)
- Severe skin reactions (Stevens-Johnson syndrome)
- Clostridioides difficile (C. diff) infection
- Blood disorders (leukopenia, thrombocytopenia)
Precautions and Contraindications
Before taking Bactrim DS 800⁄160, patients should inform their healthcare provider about:
- Allergies to sulfonamide medications
- History of liver or kidney disease
- Pregnancy or breastfeeding
- Concurrent use of other medications (e.g., warfarin, phenytoin)
Contraindications include:
- Known hypersensitivity to sulfamethoxazole or trimethoprim
- Severe liver or kidney impairment
- History of Stevens-Johnson syndrome or toxic epidermal necrolysis
| Medication Class | Description |
|---|---|
| Antibiotic | Inhibits bacterial growth |
| Sulfonamide | Interferes with folic acid synthesis in bacteria |
Key Points
- Bactrim DS 800/160 is a combination antibiotic used to treat various bacterial infections.
- Common side effects include nausea, diarrhea, and abdominal pain.
- Severe side effects may include allergic reactions, C. diff infection, and blood disorders.
- Patients with allergies to sulfonamide medications or history of liver/kidney disease should exercise caution.
- Contraindications include known hypersensitivity and severe liver/kidney impairment.
Dosage and Administration
The recommended dosage of Bactrim DS 800⁄160 varies depending on the type and severity of the infection. Typically, the adult dosage is one double-strength tablet (800⁄160 mg) every 12 hours for 10-14 days.
Overdose and Missed Dose
In case of overdose, patients should seek immediate medical attention. If a dose is missed, it should be taken as soon as possible. However, if the next dose is near, the missed dose should be skipped.
What is Bactrim DS 800/160 used for?
+Bactrim DS 800/160 is used to treat various bacterial infections, including urinary tract infections, respiratory infections, and certain types of diarrhea.
What are the common side effects of Bactrim DS 800/160?
+Common side effects include nausea, diarrhea, abdominal pain, headache, and dizziness.
Can I take Bactrim DS 800/160 if I am pregnant or breastfeeding?
+Patients should inform their healthcare provider about pregnancy or breastfeeding before taking Bactrim DS 800/160, as it may affect the fetus or baby.
In conclusion, Bactrim DS 800⁄160 is an effective antibiotic combination used to treat various bacterial infections. However, patients should be aware of potential side effects and precautions to ensure safe and effective treatment. As a healthcare professional, it is crucial to carefully evaluate patients and provide personalized guidance to optimize treatment outcomes.