Lomaira, a medication approved by the FDA in 2016, is a combination of phentermine and topiramate, used for the treatment of obesity in adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition. As with any medication, it's essential to be aware of the potential side effects of Lomaira. In this article, we'll explore the common and less common side effects of Lomaira, as well as some important safety considerations.
The active ingredients in Lomaira, phentermine and topiramate, work together to help reduce hunger and increase feelings of fullness. Phentermine, a stimulant, helps suppress appetite, while topiramate, an anticonvulsant, helps regulate food intake. The combination of these two ingredients has been shown to be effective in promoting weight loss in clinical trials.
Common Side Effects of Lomaira
The most common side effects of Lomaira are generally mild and temporary. These include:
- Dizziness (reported in 10.4% of patients)
- Headache (reported in 8.2% of patients)
- Fatigue (reported in 7.5% of patients)
- Nausea (reported in 7.2% of patients)
- Dry mouth (reported in 6.8% of patients)
These side effects are usually mild and temporary, but if they persist or worsen, it's essential to consult with your healthcare provider.
Tingling or Numbness in the Hands and Feet
Some patients taking Lomaira may experience tingling or numbness in their hands and feet, a condition known as paresthesia. This side effect was reported in 4.3% of patients in clinical trials. If you experience this symptom, it's crucial to discuss it with your healthcare provider, as it may be a sign of a more serious condition.
| Common Side Effects | Reported Frequency |
|---|---|
| Dizziness | 10.4% |
| Headache | 8.2% |
| Fatigue | 7.5% |
| Nausea | 7.2% |
| Dry mouth | 6.8% |
Less Common but More Serious Side Effects
While rare, Lomaira can cause more serious side effects, including:
Cardiovascular problems, such as increased heart rate and blood pressure, which can lead to heart attack, stroke, and cardiac arrhythmias. In clinical trials, the incidence of cardiovascular events was 1.1% in patients taking Lomaira, compared to 0.4% in patients taking placebo.
Mental health changes, such as depression, anxiety, and mood changes. In clinical trials, 2.1% of patients taking Lomaira reported depression, compared to 0.8% of patients taking placebo.
Eye problems, including glaucoma and vision changes. In clinical trials, 0.5% of patients taking Lomaira reported glaucoma, compared to 0.1% of patients taking placebo.
Sleep apnea, a condition characterized by pauses in breathing during sleep. In clinical trials, 0.8% of patients taking Lomaira reported sleep apnea, compared to 0.3% of patients taking placebo.
Contraindications and Precautions
Lomaira is contraindicated in patients with:
- Glaucoma
- History of heart attack or stroke
- Uncontrolled high blood pressure
- Hyperthyroidism
- History of substance abuse
Additionally, Lomaira should be used with caution in patients with:
- History of depression or mental health conditions
- Sleep apnea
- Kidney or liver disease
- Diabetes
Key Points
- Lomaira is a combination medication used for the treatment of obesity in adults.
- Common side effects of Lomaira include dizziness, headache, fatigue, nausea, and dry mouth.
- Less common but more serious side effects of Lomaira include cardiovascular problems, mental health changes, eye problems, and sleep apnea.
- Lomaira is contraindicated in patients with glaucoma, history of heart attack or stroke, uncontrolled high blood pressure, hyperthyroidism, and history of substance abuse.
- Patients taking Lomaira should closely monitor their side effects and report any concerns to their healthcare provider.
Conclusion
In conclusion, Lomaira is a medication that can be effective in promoting weight loss in adults with obesity. However, it's essential to be aware of the potential side effects of Lomaira, including common and less common side effects. By closely monitoring side effects and reporting any concerns to your healthcare provider, you can minimize the risks associated with Lomaira and achieve a healthy weight.
What are the most common side effects of Lomaira?
+The most common side effects of Lomaira include dizziness, headache, fatigue, nausea, and dry mouth.
Can Lomaira cause cardiovascular problems?
+Yes, Lomaira can cause cardiovascular problems, including increased heart rate and blood pressure, which can lead to heart attack, stroke, and cardiac arrhythmias.
Is Lomaira safe for patients with a history of depression?
+Lomaira should be used with caution in patients with a history of depression or mental health conditions.
Can Lomaira cause eye problems?
+Yes, Lomaira can cause eye problems, including glaucoma and vision changes.
What should I do if I experience side effects while taking Lomaira?
+If you experience side effects while taking Lomaira, you should report them to your healthcare provider immediately.